Intensity Modulated Radiotherapy (IMRT) and Intensity Modulated Stereotactic Radiotherapy (IMSRT)

Research and develop new techniques in treatment planning, dose verification treatment delivery and quality assurance in IMRT and IMSRT using dynamic MLC and mMLC. Study and evaluate the dosimetric advantages of these new treatment modalities over conventional treatments. Develop accurate and practical implementation procedures and workflow. Support clinical trials.

Dosimetry Verification and QA

Development of software and hardware tools for efficient and reliable dosimetry verification and QA of IMRT/IMSRT treatments. Development of special dosimetry phantoms dedicated for IMRT and IMSRT and other precision RT treatments for commissioning, testing and verification of such treatment.

Organ Dose Constrain-based Inverse Planning Optimization

Development of mathematical models based on organ dose constrain parameters for efficient dose optimization in inverse treatment planning

Image Guided Motion Compensated Radiotherapy

Research and develop treatment and dose planning techniques and dose verification and QA procedures for motion compensated radiotherapy. Feasibility study and dosimetry evaluation of high precision conformal RT treatment of moving target structures based on 4-D CT images and gated dose delivery system.

Monte-Carlo Simulation

Application of Monte-Carlo calculation technique on radiation dosimetry studies, verification and evaluation of treatment plans.

MR Spectroscopy and Functional MRI

Development of the physics tools to facilitate practical MRS and fMRI imaging and the data analytical tools for diagnosis and post-treatment monitoring of cancer diseases.

A Monte Carlo Calculation of the radiation dose distribution of a dynamic IMRT treatment beam. The mathematical technique is particularly useful for validation of treatments of highly inhomogeneous tissue structures.

A virtual verification system developed by Medical Physics Unit for efficient dosimetry verification of IMRT and IMSRT treatments.

A 3-D display of the dosimetry distribution of an optimized nasopharyngeal carcinoma treatment delivered by dynamic IMRT technique. The prescription dose represented by the white mess covers the red target precisely.

Diagram showing dosimetry distribution of a nasopharyngeal carcinoma treatment delivered by dynamic IMSRT technique. The prescription dose indicated in green is delivered to conform closely the treatment target which is represented by the red line.

Development of new tools to test and verify new clinical innovations- a physics staff assessing and testing a new IMSRT dosimetry phantom developed by MPU. The stereotactic head phantom can be mounted in treatment position to simulate exactly patient treatment.

Multidisciplinary supports for clinical research and development- a Technician making a test phantom for dosimetry studying of lung treatment.