(TRA016) The Immunological Mechanism of Plasma EBV DNA Clearance during Radiotherapy in Patients with Nasopharyngeal Carcinoma-a pilot study
Chair:
Prof. Brigette Ma
Eligibility:
Adult patients with histologically confirmed non-keratinizing nasopharyngeal carcinoma previously untreated and are planned for curative treatment.
Objectives:
To investigate changes in T-cell mediated immune response in patients undergoingRT alone or concurrent chemoradiotherapy (CRT) for nasopharyngeal carcinoma(NPC).
(TRA025) Impact of Radiotherapy on the Dynamic Changes of Circulating Cell-free DNA in Patients with Hepatocellular Carcinoma
Chair:
Dr. Landon Chan
Eligibility:
Histologically proven hepatocellular cancer patients who are planning on undergoing SBRT for HCC. Patient should also have adequate haematologic, renal and hepatic function.
Objectives:
To characterize the temporal changes of the biological properties of ctDNA, including its relative percentage, fragment size, and end-motif fragment pattern (i.e. jaggedness) for patients undergoing SBRT to HCC.